In June 2019, Chapelier was one of five members of the LREM parliamentary group who joined a cross-party initiative to legalize the distribution and use of cannabis.

In July 2019, Chapelier voted in favor of the French ratification of the European Union’s Comprehensive Economic and Trade Agreement (CETA) with Canada.

In 2018, Chapelier joined other co-signatories around Sébastien Nadot in officially filing a request for a commission of inquiry into the legality of French weapons sales to the Saudi-led coalition fighting in Yemen, days before an official visit of Saudi Crown Prince Mohammed bin Salman to Paris.

Annie Chapelier (born 7 November 1967) is a French nurse anesthetist and politician who has been serving as a member of the French National Assembly since the 2017 elections, representing the department of Gard. From 2017 until 2020, she was a member of La République En Marche! (LREM). In May 2020, she was one of the 17 initial members of the Ecology Democracy Solidarity group.