Ghassan Hitto (Arabic: غسان هيتو ‎; born 1963) was the first head of an interim government established by the Syrian opposition National Coalition. Born in Damascus into a Kurdish family, he left Syria to the U.S. in 1980, became a naturalized American citizen and worked as an information technology executive and lived in Texas until recently. In late 2012, he relocated to Turkey. He was elected prime minister on 18 March 2013 by a narrow margin over former Syrian Arab Republic agricultural minister Assad Mustafa. Hitto resigned on 8 July 2013.

Hitto is a former businessman who has lived in the United States for decades, most recently in Murphy, Texas. Before joining the opposition, he worked with Inovar, a Telecommunication firm, from 2001 to 2012.

Hitto is married to Suzanne Hitto, an American schoolteacher; they have four children, Amer, Imran, Obaida, Lama all born in the United States. He has worked in the technology sector and supported the private school Brighter Horizons Academy founded in 1989 by the Islamic Services Foundation (ISF). He is also a founding member of the Muslim Legal Fund of America created after the 11 September 2001 attacks to give legal aid to Muslims.

Hitto graduated from Indiana University-Purdue University at Indianapolis in 1989 with degrees in mathematics and computer science. He also received an M.B.A. at Indiana Wesleyan University in 1994.